Training Data

Rich Sutton and Khurram Javed: Why AI Models Stop Learning, and How to Start It Again

Rich Sutton, who helped pioneer reinforcement learning and wrote the seminal AI essay The Bitter Lesson, has now cofounded Oak Lab with his former student Khurram Javed. Their goal: to build agents th...

2026-08-18

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Chai Discovery's Bitter Lesson: Drug Design Is Another Scaling Problem

Most people treat biology as a bespoke, messy science. Josh Meier and Matt McPartlon, co-founders of Chai Discovery, treat it as an engineering problem. They make the case that drug design obeys the b...

2026-08-04

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Building the Automated AGI Lab: Core Automation's Jerry Tworek and Rohan Anil

Jerry Tworek led reasoning at OpenAI, convinced that scaling reinforcement learning was the path to AGI. Rohan Anil co-led Gemini pre-training and built the Shampoo optimizer. Now they've teamed up at...

2026-07-29

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Factory's Matan Grinberg: The Coming ‘Dark Factory’ Where Software Builds Itself

Factory started building fully autonomous coding agents in April 2023, two years before enterprises were ready. Matan Grinberg now says this is indistinguishable from being wrong. The Factory co-found...

2026-07-21

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Anthropic's Katelyn Lesse & Angela Jiang: Building an Ecosystem, not a Walled Garden

Katelyn Lesse and Angela Jiang lead the team building Anthropic's developer platform - the layer that both outside builders and Anthropic's own products run on top of. Angela frames the platform as a ...

2026-07-14

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Inside Zipline's Autonomous System: 140M Miles, Zero Incidents

The largest commercial autonomous system on earth isn't a robotaxi fleet — it's Zipline, which has flown 140 million autonomous miles with zero safety incidents. Co-founder Keller Rinaudo Cliffton and...

2026-07-07

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Why Hardware-Software Co-Design Is AI's Real 100x: Dylan Patel of SemiAnalysis

Dylan Patel, founder of SemiAnalysis, argues the biggest gains in AI don't come from faster chips, they come from software-hardware co-design. Optimizing the model, the kernels, and the silicon togeth...

2026-06-30

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Memory and Continual Learning: Engram's Dan Biderman and Jessy Lin

Dan Biderman and Jessy Lin, co-founders of Engram, are building a neolab around memory and continual learning, which they call two sides of the same coin. Their contrarian premise: instead of stuffing...

2026-06-24

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Simulating Humans at Scale: Simile's Joon Sung Park

The race to build superintelligence is producing models that keep getting better at objective problems, but not at behaving like actual people. Joon Sung Park, founder and CEO of Simile and creator of...

2026-06-16

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Google DeepMind's Logan Kilpatrick: Why the Model Eats the Harness

The entire startup ecosystem is racing to build agent harnesses. Logan Kilpatrick, who leads Google AI Studio and the Gemini API, argues that scramble has a roughly 12-month shelf life. Models will ab...

2026-06-11

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LIVE: Jensen Huang on Building the Dynamo of the Intelligence Age

Jensen Huang, founder and CEO of NVIDIA, makes the case that computing is undergoing its biggest shift in 60 years: from retrieval, where data centers store files we look up, to generation, where ever...

2026-06-10

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Knowing What Your Customers Want, All the Time: Listen Labs' Alfred Wahlforss

Alfred Wahlforss, co-founder and CEO of Listen Labs, is building an AI agent that interviews your customers at a scale no focus group ever could—thousands of voice conversations at once, drawn from an...

2026-06-02

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How Cursor Trained Composer on Fireworks: Distributed Infrastructure for High-Performance RL

Cursor's Federico Cassano and Fireworks' Dmytro Dzhulgakov explain how they collaborated to build Composer as a specialized foundation model. The core insight: models have finite capacity in their wei...

2026-05-26

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Rebuilding IT From the Ground Up for the AI Age: Serval's Jake Stauch

Jake Stauch, founder and CEO of Serval, is building a ServiceNow for the AI era. His most contrarian bet is that the product should look like boring old enterprise software, but with unlimited intelli...

2026-05-19

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Suno's Mikey Shulman: Everyone Can Make Music Now

Most music platforms assume you're a listener. On Suno, 90% of daily users make something. Founder and CEO Mikey Shulman explains why that flips the model: the act of creating IS the entertainment, w...

2026-05-14

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ElevenLabs' Mati Staniszewski: How Voice Becomes the Interface for Everything

Mati Staniszewski, co-founder and CEO of ElevenLabs, joins Sequoia partner Andrew Reed at AI Ascent 2026 to talk about how a four-year-old company built a frontier audio AI business with just over 400...

2026-05-09

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Anthropic's Boris Cherny: Coding's Printing Press Moment

Boris Cherny, creator of Claude Code at Anthropic, joins Sequoia partner Lauren Reeder at AI Ascent 2026 to talk about where coding goes from here. He explains why he hasn't written a line of code in ...

2026-05-05

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Waymo's Dmitri Dolgov: 20 Million Rides and the Road to Full Autonomy

Dmitri Dolgov, co-CEO of Waymo, joins Sequoia partner Konstantine Buhler at AI Ascent 2026 to talk about the 20-year arc from the DARPA Grand Challenge to fully autonomous service in eleven cities and...

2026-05-05

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OpenAI's Greg Brockman: Why Human Attention Is the New Bottleneck

Greg Brockman, co-founder and president of OpenAI, joins Sequoia partner Alfred Lin at AI Ascent 2026 for a conversation that spans the full OpenAI stack. He explains why the company will never have e...

2026-05-02

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Demis Hassabis on Building DeepMind, AlphaFold, and the Final Stretch to AGI

Demis Hassabis, co-founder and CEO of Google DeepMind and 2024 Nobel laureate in chemistry for AlphaFold, joins Sequoia partner Konstantine Buhler at AI Ascent 2026 for a wide-ranging conversation abo...

2026-05-01

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